The role of hsp 70 in the implementation of neuroprotective effect of selective estrogen receptor modulator (serm) in deprivation of the system`s level of restored glutathione in vitro6
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Запорізький державний медичний університет
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The aim of the research: to determine the value of the heat shock protein HSP 70 in the implementation of the mechanism of neuroprotective actions of selective estrogen receptor modulator (SERM) – (Z)-2-[4-(1,2-diphenyl-1-butenil)fenoxy]-N, N-dimethilaethanamin citrate. The objective of this study was to estimate the influence of SERM on the expression of HSP70, the activity of the thiol-disulfide system of neurons and mitochondria development of neuronal apoptosis in vitro, with a deficit of restored glutathione.
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The role of hsp 70 in the implementation of neuroprotective effect of selective estrogen receptor modulator (serm) in deprivation of the system`s level of restored glutathione in vitro6 / I. F. Belenichev, A. A. Egorov, E. Zaporozhchenko, O. Ryzhenko // Актуальні питання сучасної медицини і фармації : тези доп. Всеукр. наук.-практ. конф. (до 50-річчя заснування ЗДМУ), 18-25 квітня 2018 р., 30 травня 2018 р. – Запоріжжя, 2018. – С. 6.