Modern trends in drug discovery process

Abstract

ABSTRACT. The number of factors that determine the biological asset the number of compounds is so great and diverse that scientists cannot use them all. It is necessary to estimate the toxicity of newly synthesized substance, its effect on various body systems and possible incompatibility for use. First, the drug-like compound must show high level of biological activity, selectivity, and duration of the therapeutic effect. It should be chemically pure and have high storage stability, and the cost of its production should not be too high. When biologically active compounds enter the body and start interaction with many cells in metabolic processes, it needs this requires careful study. Most of the metabolic processes of drugs in the body are processes of their inactivation. However, in some cases, in the process of metabolic transformations, compounds with higher biological activity are formed.