A Simple and Convenient Method for the Synthesis of 1-Methyl-7-arylfuro[3,2-g]pteridine-2,4(1H,3H)-diones and Their Substituted Derivatives

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dc.contributor.authorKazunin, M. S.
dc.contributor.authorVoskoboynik, O. Yu.
dc.contributor.authorShishkina, S. V.
dc.contributor.authorAntypenko, O. M.
dc.contributor.authorKovalenko, S. I.
dc.contributor.authorКазунін, Максим Станіславович
dc.contributor.authorВоскобойнік, Олексій Юрійович
dc.contributor.authorШишкіна, С. В.
dc.contributor.authorАнтипенко, Олексій Миколайович
dc.contributor.authorКоваленко, Сергій Іванович
dc.date.accessioned2021-06-18T07:41:02Z
dc.date.available2021-06-18T07:41:02Z
dc.date.issued2020
dc.description.abstractA simple and effective method for the synthesis of unknown 1-methyl-7-arylfuro[3,2-g]pteridine-2,4(1H,3H)-diones by dehydration of the corresponding 1-methyl-6-phenacyl-pteridine-2,4,7(1H,3H,8H)-triones is reported in the article. It was shown that their alkylation by butyl chloroacetate in basic medium proceeded by the N3-atom of the heterocycle. The structure and purity of the synthesized compounds were confirmed by IR, 1H, 13C NMR spectroscopy, gas chromatography-mass spectrometry, mass spectrometry, as well as X-ray diffraction analysis. The proposed mechanism of the dehydration reaction was discussed.uk_UK
dc.identifier.citationA simple and convenient method for the synthesis of 1-methyl-7-arylfuro[3,2-g]pteridine-2,4(1H,3H)-diones and their substituted derivatives / M. S. Kazunin, O. Yu. Voskoboynik, S. V. Shishkina, O. M. Antypenko, S. I. Kovalenko // Acta Chimica Slovenica. - 2020. - Vol. 67, № 2. -P. 586-593. - https://doi.org/10.17344/ACSI.2019.5601.uk_UK
dc.identifier.urihttps://zsmu.rosbai.com/handle/123456789/14061
dc.language.isoenuk_UK
dc.subject1-methyl-6-(2-oxo-2-arylethyl)pteridine-2,4,7(1H,3H,8H)-trionesuk_UK
dc.subjectdehydrationuk_UK
dc.subject1-methyl-7-arylfuro[3,2-g] pteridine-2,4(1H,3H)-dionesuk_UK
dc.subjectalkylationuk_UK
dc.subjectX-ray diffraction analysisuk_UK
dc.titleA Simple and Convenient Method for the Synthesis of 1-Methyl-7-arylfuro[3,2-g]pteridine-2,4(1H,3H)-diones and Their Substituted Derivativesuk_UK
dc.typeArticleuk_UK

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