Synthesis of novel ylidenhydrazides of 3-benzyl-8-methylxanthinyl-7-acetic acid as potential biological active compounds

Abstract

In this work, we have described the method of 3-benzyl-8-methylxanthinyl-7-acetohydrazide synthesis and studied its reaction with different aldehydes and ketones in acidic medium. As result, we obtained a series of novel ylidenhydrazides of 3-benzyl-8-methylxanthinyl-7-acetic acid. The structure of the synthesized substances was proved by IR and NMR spectra and elemental analysis and their individuality was confirmed by thin-layer chromatography.