A study of the antimicrobial and fungicidal activity of a potentially new combined tablet preparation based on decamethoxin and thiotriazolin

Abstract

Today, diseases caused by pathogenic bacteria are the most dangerous, as they can not only affect the quality of human life, but also lead to death. According to WHO, pathogenic bacteria. namely, mycoses affect from 1/5 to 1/3 of the world's population, more than a third (37.8%) of them cause yeast-like (Candida). Over the past 20 years, there has been a 15-fold increase in the frequency of infectious inflammatory diseases of candidiasis etiology. After analyzing the assortment of drugs that are used for diseases of the mucous membrane of the oral cavity, in the domestic pharmaceutical market. It was found that, for these diseases, the choice of drugs is very limited, and drugs of foreign origin are on the list of most used drugs. All of the above shows the need to create a new domestic drug, namely tablets for resorption, exhibiting antimicrobial, fungicidal, activity. Based on the foregoing, the goal of our work is to create a new drug, namely tablets based on decamethoxin (exhibiting antimicrobial) and an antioxidant - thiotriazolin.