Efficiency of cortexin under the conditions of experimental chronic brain ischemia
| dc.contributor.author | Demchenko, A. V. | |
| dc.contributor.author | Belenichev, I. F. | |
| dc.contributor.author | Демченко, Аліна Вікторівна | |
| dc.contributor.author | Бєленічев, Ігор Федорович | |
| dc.date.accessioned | 2018-05-04T11:12:51Z | |
| dc.date.available | 2018-05-04T11:12:51Z | |
| dc.date.issued | 2016 | |
| dc.description.abstract | Chronic brain ischemia was accompanied by decreased activities of glutathione-dependent enzymes and an increased content of nitrotyrosine in the rat brain, which indicates the development of oxidative and nitrosative stress and a decline of cognitive functions. Treatment with cortexin normalized the activities of glutathione-dependent enzymes, increased the contents of intermediates of the thiol–disulfide system, decreased the level of nitrotyrosine, which is a marker of nitrosative stress, and improved memory. | uk_UK |
| dc.identifier.citation | Demchenko A. V. Efficiency of cortexin under the conditions of experimental chronic brain ischemia / A. V. Demchenko I. F. Belenichev // Neurochemical Journal. – 2016. – Vol. 10, №. 1. – P. 64-68. DOI: 10.1134/S1819712416010050 | uk_UK |
| dc.identifier.uri | https://zsmu.rosbai.com/handle/123456789/7658 | |
| dc.language.iso | en | uk_UK |
| dc.publisher | Pleiades Publishing | uk_UK |
| dc.subject | chronic brain ischemia | uk_UK |
| dc.subject | thiol–disulfide system | uk_UK |
| dc.subject | glutathione | uk_UK |
| dc.subject | nitrotyrosine | uk_UK |
| dc.subject | cognitive functions | uk_UK |
| dc.subject | cortexin | uk_UK |
| dc.title | Efficiency of cortexin under the conditions of experimental chronic brain ischemia | uk_UK |
| dc.type | Article | uk_UK |