In water multicomponent synthesis of low-molecular-mass 4,7-dihydrotetrazolo[1,5-a]pyrimidines
| dc.contributor.author | Tkachenko, I. G. | |
| dc.contributor.author | Komykhov, S. A. | |
| dc.contributor.author | Musatov, V. I. | |
| dc.contributor.author | Shishkina, S. V. | |
| dc.contributor.author | Dyakonenko, V. V. | |
| dc.contributor.author | Shvets, V. N. | |
| dc.contributor.author | Diachkov, M. V. | |
| dc.contributor.author | Chebanov, V. A. | |
| dc.contributor.author | Desenko, S. M. | |
| dc.contributor.author | Швець, Володимир Миколайович | |
| dc.date.accessioned | 2022-01-17T11:09:40Z | |
| dc.date.available | 2022-01-17T11:09:40Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | The three-component reaction of 5-aminotetrazole with aliphatic aldehydes (formaldehyde, acetaldehyde) and acetoacetic ester derivatives in water under microwave irradiation leads to the selective formation of 4,7-dihydrotetrazolo[1,5-a]pyrimidine derivatives. Under similar conditions using 4,4,4-trifluoroacetoacetic ester 5-hydroxy-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidines are obtained. The analogous reaction with acetylacetone requires scandium(III) triflate as catalyst. The antioxidant activity of selected compounds was assayed with 1,1-diphenyl-2-picrylhydrazyl. | uk_UK |
| dc.identifier.citation | In water multicomponent synthesis of low-molecular-mass 4,7-dihydrotetrazolo[1,5-a]pyrimidines / I. G. Tkachenko, S. A. Komykhov, V. I. Musatov, S. V. Shishkina, V. V. Dyakonenko, V. N. Shvets, M. V. Diachkov, V. A. Chebanov, S. M. Desenko // Beilstein Journal of Organic Chemistry. - 2019. - № 15. - P. 2390-2397. - https://doi.org/10.3762/bjoc.15.231. | uk_UK |
| dc.identifier.uri | https://zsmu.rosbai.com/handle/123456789/15930 | |
| dc.language.iso | en | uk_UK |
| dc.subject | 5-aminotetrazole | uk_UK |
| dc.subject | antioxidant activity | uk_UK |
| dc.subject | 1,3-dicarbonyl compounds | uk_UK |
| dc.subject | multicomponent synthesis | uk_UK |
| dc.subject | tetrazolo[1,5-a]pyrimidines | uk_UK |
| dc.title | In water multicomponent synthesis of low-molecular-mass 4,7-dihydrotetrazolo[1,5-a]pyrimidines | uk_UK |
| dc.type | Article | uk_UK |