Correlation between plasma α-synuclein and glutathione peroxidase levels in early stages of Parkinson’s disease

Abstract

Introduction. Parkinson’s disease (PD) is a progressive neurodegenerative disorder, which is defined as one of the synucleopathies. It is also known that oxidative stress is associated with α-synuclein amyloidogenesis in PD pathogenesis. The aim of this study was to investigate possible correlations between α-synuclein and glutathione peroxidase (GPx), as the biomarker of oxidative stress, in early stages of PD.