Effectiveness of conservative and surgical treatment of acute pancreatitis of severe nutritional etiology

Abstract

Objective. To analyze the results of treatment of patients with severe acute pancreatitis of alimentary etiology. Materials and methods. The retrospective analysis included 35 case histories of patients with severe acute pancreatitis of alimentary etiology who were treated in the surgical departments of the Zaporizhzhia City Emergency and Ambulance Hospital from January 2023 to September 2024. Results. Against the background of the treatment, 29 (82.86%) patients were discharged with improvement for continuation of conservative therapy and observation in outpatient settings. Six (17.14%) patients died. Among the deceased, 5 (83.33%) underwent surgical treatment. Postoperative mortality in severe acute pancreatitis of alimentary etiology was 31.25%, while mortality in unoperated patients was 5.26% (p = 0.0048, U = 112.5). Conclusions. Treatment of patients with severe acute pancreatitis of alimentary etiology based on a personalized approach using multisurgical methods combined with individually targeted conservative therapy will have better results, which will be reflected in a reduction in the frequency of postoperative complications and mortality rates.