Expression of the water channel protein AQUAPORIN-4 in the brain during human liver cirrhosis
| dc.contributor.author | Shuliatnikova, T. V. | |
| dc.contributor.author | Tumanskyi, V. O. | |
| dc.contributor.author | Шулятнікова, Тетяна Володимирівна | |
| dc.contributor.author | Туманський, Валерій Олексійович | |
| dc.date.accessioned | 2023-01-20T08:49:56Z | |
| dc.date.available | 2023-01-20T08:49:56Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Hepatic encephalopathy (HE) is a frequent complication of liver cirrhosis, manifesting as a neuropsychiatric syndrome ranging from cognitive deficits to coma. HE pathophysiology is linked to elevated brain ammonia and neuroinflammation [1]. Astrocytes are central brain cells responsible for ammonia detoxification and during acute HE are characterized by severe swelling [1]. Aquaporin-4 (AQP4) is a central protein of astrocytes, predominant water channel in the brain, which undergo alteration in response to hyperammonemia [2]. | uk_UK |
| dc.identifier.citation | Shuliatnikova, T. V. Expression of the water channel protein AQUAPORIN-4 in the brain during human liver cirrhosis / T. V. Shuliatnikova, V. O. Tumanskyi // Grail of Science : proceedings of the IV International Scientific and Practical Conference "Science of post-industrial society: globalization and transformation processes". - Vinnytsia, 2022. - N 22. - P. 287-288. - https://doi.org/10.36074/grail-of-science.25.11.2022.53. | uk_UK |
| dc.identifier.uri | https://zsmu.rosbai.com/handle/123456789/17919 | |
| dc.language.iso | en | uk_UK |
| dc.title | Expression of the water channel protein AQUAPORIN-4 in the brain during human liver cirrhosis | uk_UK |
| dc.type | Article | uk_UK |