Dose-dependent efficacy and safety of drugs in patients with chronic heart failure?
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Treatment of chronicheart failure(CHF) is very controversial. The question of optimal doses of beta-blockers, ACE inhibitors, aldosterone receptor antagonists, statins in patients with CHF hadn’t been definitively resolved. Achieving the maximum tolerated doses of drugs, although associated with reduced mortality, but is accompanied by an increase in side effects of drugs.
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Lysenko V. A. Dose-dependent efficacy and safety of drugs in patients with chronic heart failure? / V. A. Lysenko ; scientific advisor V.V. Syvolap // Scientific collection “Interconf” : proceedings of the 9th International Scientific and Practical Conference (July 16-18, 2021) at Washington, USA. - Washington : endeavours Publisher, 2021. - № 66 : Challenges in science of nowadays. - P. 358-359.