Approaches to pharmacological correction of psychophysiological stress in athletes

Abstract

The aim of the study was to assess the effectiveness of the influence of the medical drug tivortin®aspartate (drinking solution of L-arginine aspartate) on the psychophysiological characteristics and the severity of psychophysiological stress in qualified athletes at the stage of direct preparation for the competition. Methodologically, the studies, which are randomized, blind, placebo-controlled, during the course (14 days) of drug usage in a daily dose of 40 ml were carried out in compliance with bioethical principles. The athletes in the control subgroups received placebo (3% glucose solution) in identical dosage, multiplicity and duration of usage. The assessment of the severity of psychophysiological stress and its individual components was carried out in a technology modified by us according to the standard questionnaire of V.A. Ivanchenko. The results obtained showed that in both control subgroups by the end of the observation period, although not too significant, but nevertheless, a significant increase in the value of the magnitude of psychophysiological stress was observed (from 38.08±1.38 to 41.67±1.71 points and from 37.52±1.24 to 39.94±0.99 points for athletes and weightlifters, respectively; in both cases changes are valid, p <0.05) and its individual components. On the contrary, in the athletes who used tivortin®aspartate in the dynamics of the study, the indicators of the severity of psychophysiological stress very significantly and reliably (from 48.67±0.69 to 39.17±1.07 in athletes and from 41.14±0, 46 to 39.97±0.79 in weightlifters; in both cases changes are valid, p <0.05) decreased, which indicated an improvement in psychological stability and a corresponding increase in mental stability to the forthcoming impact of competitive loads. In this way, the data obtained indicate an improvement in the mental readiness of athletes for the upcoming competitions and substantiate the advisability of using pharmacological substances based on L-arginine to improve psychophysiological characteristics during physical exertion with a different mechanism of energy supply.