Molecular docking of 5-phenyl-5,6-dihydrotetrazolo-[1,5-c]quinazolines to ribosomal 50s protein L2P (2QEX

dc.contributor.authorAntypenko, O. M.
dc.contributor.authorAntypenko, L.
dc.contributor.authorKalnysh, D.
dc.contributor.authorKovalenko, S. I.
dc.contributor.authorАнтипенко, Олексій Миколайович
dc.contributor.authorКоваленко, Сергій Іванович
dc.date.accessioned2022-11-03T12:37:52Z
dc.date.available2022-11-03T12:37:52Z
dc.date.issued2022
dc.descriptionAntypenko O. M. - https://orcid.org/0000-0002-8048-445X; Kovalenko S. I. - https://orcid.org/0000-0001-8017-9108.uk_UK
dc.description.abstractGiven the presence of antimicrobial activity for various tetrazole derivatives and its condensed analogues, it was proposed to analyze 13 novel 5-phenyl-5,6-dihydrotetrazolo[1,5-c]quinazolines for molecular docking to ribosomal 50S protein L2P (2QEX) in comparison with Tedizolid, tetrazole-oxazolidinone antibiotic. Hence, 4-(5-methyl-5,6-dihydrotetrazolo[1,5-c]-quinazolin-5-yl)benzoic acid 12 proved to be the most probable in terms of antimicrobial activity in vitro as a result of in silico molecular docking to antimicrobial 2QEX target.uk_UK
dc.identifier.citationMolecular docking of 5-phenyl-5,6-dihydrotetrazolo-[1,5-c]quinazolines to ribosomal 50s protein L2P (2QEX) / O. Antypenko, L. Antypenko, D. Kalnysh, S. Kovalenko // Міжнародний науковий журнал «Грааль науки». – 2022. - № 12-13.- С. 693-698.uk_UK
dc.identifier.urihttps://zsmu.rosbai.com/handle/123456789/17560
dc.language.isoenuk_UK
dc.subject5-phenyl-5,6-dihydrotetrazolo[1,5-c]quinazolinesuk_UK
dc.subjectmolecular dockinguk_UK
dc.subjectribosomal 50S protein L2P (2QEX)uk_UK
dc.titleMolecular docking of 5-phenyl-5,6-dihydrotetrazolo-[1,5-c]quinazolines to ribosomal 50s protein L2P (2QEXuk_UK
dc.typeArticleuk_UK

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
c693-698.pdf
Size:
445.04 KB
Format:
Adobe Portable Document Format

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
2.13 KB
Format:
Plain Text
Description: