Synthesis of 5-R-4-R1-3-alkylthio-1,2,4-triazoles and study influence of their adsorption ability on the results of toxicity and anti-hypoxic activity
| dc.contributor.author | Kucheryavyi, Yu. M. | |
| dc.contributor.author | Kaplaushenko, A. G. | |
| dc.contributor.author | Korzhova, A. S. | |
| dc.contributor.author | Кучерявий, Юрій Миколайович | |
| dc.contributor.author | Каплаушенко, Андрій Григорович | |
| dc.contributor.author | Коржова, Алла Станіславівна | |
| dc.date.accessioned | 2022-11-14T07:44:12Z | |
| dc.date.available | 2022-11-14T07:44:12Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | During our research of biologically active substances we have synthesized series of new 5-R-4-R1-3-alkylthio-1,2,4- triazoles for original drugs creation. 14 new compounds have been synthesized in total. The structure of it has been confirmed by a complex of modern physical and chemical methods of analysis. For these compounds the data of toxicity, anti-hypoxic activity, surface activity and adsorption ability has been set. The obtained results of biological activity have been compared with data of adsorption properties of 1,2,4-triazoles derivatives to establish structureaction regularity. | uk_UK |
| dc.identifier.citation | Kucheryavyi Yu. M. Synthesis of 5-R-4-R1-3-alkylthio-1,2,4-triazoles and study influence of their adsorption ability on the results of toxicity and anti-hypoxic activity / Yu. M. Kucheryavyi, A. G. Kaplaushenko, A. S. Korzhova // The pharma innovation - journal. - 2014. - Vol. 3, No. 1. - С. 69-73. | uk_UK |
| dc.identifier.uri | https://zsmu.rosbai.com/handle/123456789/17628 | |
| dc.language.iso | en | uk_UK |
| dc.subject | 1,2,4-triazoles | uk_UK |
| dc.subject | physical and chemical properties | uk_UK |
| dc.subject | susceptibility to adsorption | uk_UK |
| dc.subject | toxicity | uk_UK |
| dc.subject | anti-hypoxic activity | uk_UK |
| dc.title | Synthesis of 5-R-4-R1-3-alkylthio-1,2,4-triazoles and study influence of their adsorption ability on the results of toxicity and anti-hypoxic activity | uk_UK |
| dc.type | Article | uk_UK |