Synthesis and antiradical activity of alkyl derivatives of 5-(5-methyl-1h-pyrazol-3-yl)-4-phenyl-4h1,2,4-triazole-3-thiol
| dc.contributor.author | Gotsulya, A. | |
| dc.contributor.author | Гоцуля, Андрій Сергійович | |
| dc.date.accessioned | 2021-08-12T11:48:48Z | |
| dc.date.available | 2021-08-12T11:48:48Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | Objective: The aim of the work was to develop effective methods for the synthesis of biologically active heterocyclic systems containing 1,2,4-triazole and pyrazole. Material and Method: Chemical structures of synthesized compounds were characterized with elemental analysis, IR, 1H-NMR, LC-MS techniques. The antiradical activity was evaluated using the 2,2-diphenyl-1- picrylhydrazyl (DPPH) radical scavenging activity assay. Result and Discussion: Developed optimal methods of obtaining of alkylderivatives of 5-(5-methyl-1Hpyrazol-3-yl)-4-phenyl-4H-1,2,4-triazole-3-thiol. A number of synthesized compounds showed moderate antiradical activity. | uk_UK |
| dc.identifier.citation | Gotsulya A. Synthesis and antiradical activity of alkyl derivatives of 5-(5-methyl-1h-pyrazol-3-yl)-4-phenyl-4h1,2,4-triazole-3-thiol / A. Gotsulya // Ankara Üniversitesi Eczacılık Fakültesi Dergisi. - 2020. - Vol. 44, Iss. 2. -P. 211-219. - https:// 10.33483/jfpau.6161161 | uk_UK |
| dc.identifier.uri | https://zsmu.rosbai.com/handle/123456789/14440 | |
| dc.language.iso | en | uk_UK |
| dc.subject | antiradical activity | uk_UK |
| dc.subject | pyrazole | uk_UK |
| dc.subject | synthesis | uk_UK |
| dc.subject | 1,2,4-triazoles | uk_UK |
| dc.title | Synthesis and antiradical activity of alkyl derivatives of 5-(5-methyl-1h-pyrazol-3-yl)-4-phenyl-4h1,2,4-triazole-3-thiol | uk_UK |
| dc.type | Article | uk_UK |