State of peroxidation processes in pregnant women with varicose disease

Abstract

Chronic venous disease is defined as a set of diseases affecting the venous system, mainly manifested in the form of varicose veins [1]. The incidence of varicose disease (VD) of the lower extremities occupies one of the leading places in the structure of somatic diseases and is found in 60% of the female population in Ukraine [2]. The probability of developing varicose disease in women with a history of pregnancy exceeds 80% [3]. The pathogenesis of VD is a complex and multifactorial process [1, 4]. The venous system changes its function during pregnancy - changes are both functional and structural [5]. However, despite the availability of numerous studies on the causes of varicose disease of the venous wall, understanding the pathogenesis of this pathological condition still remains many questions [6].