Investigation of the acute toxicity of new xanthine xenobiotics with noticeable antioxidant activity

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dc.contributor.authorVasylyev, D.
dc.contributor.authorPriimenko, B.
dc.contributor.authorAleksandrova, K.
dc.contributor.authorMykhalchenko, Y.
dc.contributor.authorGutyj, B.
dc.contributor.authorMazur, I.
dc.contributor.authorMagrelo, N.
dc.contributor.authorSus, H.
dc.contributor.authorDashkovskyy, O.
dc.contributor.authorVus, U.
dc.contributor.authorKamratska, O.
dc.contributor.authorВасильєв, Денис Андрійович
dc.contributor.authorАлександрова, Катерина Вячеславівна
dc.date.accessioned2021-05-27T06:15:12Z
dc.date.available2021-05-27T06:15:12Z
dc.date.issued2021
dc.description.abstractOver the last few decades, there was significant interest in applying various xanthine derivatives to treat several diseases as highly potent antioxidant agents. Our study introduced several pharmacophore groups in the xanthine core to improve its antioxidant activity and increase biological fluids' solubility. We synthesized a set of new low-toxic 3-methylxanthine derivatives. Such compounds bear challenging scaffolds for finding effective antioxidant agents with broad application in medicine and pharmacy.uk_UK
dc.identifier.citationInvestigation of the acute toxicity of new xanthine xenobiotics with noticeable antioxidant activity / D. Vasylyev, B. Priimenko, K. Aleksandrova, Y. Mykhalchenko, B. Gutyj, I. Mazur, N. Magrelo, H. Sus, O. Dashkovskyy, U. Vus, O. Kamratska // Ukrainian Journal of Ecology. - 2021. - Vol. 11, № 1. – P. 315-318. - https://doi.org/10.15421/2021_47uk_UK
dc.identifier.urihttps://zsmu.rosbai.com/handle/123456789/13764
dc.language.isoenuk_UK
dc.subjectreactive oxygen speciesuk_UK
dc.subject3-methylxanthine derivativesuk_UK
dc.subjectantioxidant activityuk_UK
dc.titleInvestigation of the acute toxicity of new xanthine xenobiotics with noticeable antioxidant activityuk_UK
dc.typeArticleuk_UK

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