Analgesic activity of 4-R-5-pyridine-1,2,4-triazole-3-thiol derivatives in the experiment

Abstract

Modern pharmaceutical science creates medicines that directly affect the causes of disease. However, the etiology of many diseases accompanied by pain has not yet been established, which does not allow to write off the drugs of symptomatic therapy, which have a depressant effect on the manifestations and symptoms of the pathological process [1, p. 1579]. The modern pharmaceutical market contains a wide range of drugs with anti-inflammatory and analgesic activity, primarily non-steroidal anti-inflammatory drugs that have a lot of side effects, including ulcerogenic action.