Adme properties prediction of 5-phenyl-5,6-dihydrotetrazolo[1,5-c] quinazolines
| dc.contributor.author | Antypenko, O. M. | |
| dc.contributor.author | Antypenko, L. | |
| dc.contributor.author | Kalnysh, D. | |
| dc.contributor.author | Kovalenko, S. I. | |
| dc.contributor.author | Антипенко, Олексій Миколайович | |
| dc.contributor.author | Коваленко, Сергій Іванович | |
| dc.date.accessioned | 2022-11-03T12:31:45Z | |
| dc.date.available | 2022-11-03T12:31:45Z | |
| dc.date.issued | 2022 | |
| dc.description | Antypenko O. M. - https://orcid.org/0000-0002-8048-445X; Kovalenko S. I. - https://orcid.org/0000-0001-8017-9108. | uk_UK |
| dc.description.abstract | Due to the recent predicted affinity of 13 novel 5-phenyl-5,6-dihydrotetrazolo[1,5-c]-quinazolines to the ribosomal 50S protein L2P (2QEX) by molecular docking, their ADME properties were calculated at the site SwissADME to predict their drug-likeness. Hence, substances 6, 10, and 12 appeared to be the leading compounds among all studied ones and are of definite interest for further in vitro antimicrobial activity investigation. | uk_UK |
| dc.identifier.citation | Adme properties prediction of 5-phenyl-5,6-dihydrotetrazolo[1,5-c] quinazolines / O. Antypenko, L. Antypenko, D. Kalnysh, S. Kovalenko // Міжнародний науковий журнал «Грааль науки». – 2022. - № 12-13.- С. 684-692. | uk_UK |
| dc.identifier.uri | https://zsmu.rosbai.com/handle/123456789/17559 | |
| dc.language.iso | en | uk_UK |
| dc.subject | ADME properties | uk_UK |
| dc.subject | 5-phenyl-5,6-dihydrotetrazolo[1,5-c]quinazolines | uk_UK |
| dc.subject | drug-likeness | uk_UK |
| dc.title | Adme properties prediction of 5-phenyl-5,6-dihydrotetrazolo[1,5-c] quinazolines | uk_UK |
| dc.type | Article | uk_UK |