The role of vitamin D in the development of anemia of inflammation in young children with acute inflammatory bacterial diseases of the respiratory system

Abstract

In the last decade, the concept of the polymodal function of vitamin D in the children's body has expanded significantly. In particular, it became known about the effect of vitamin D on the synthesis of the antimicrobial peptide hepcidin, a marker of iron metabolism, which implements a protective function by reducing the bioavailability of iron, necessary for the growth of bacterial pathogens. We can assume an interconnection between vitamin D content in the blood serum and the risk of anemia of inflammation, the leading mechanism of which includes the induction of hepcidin by pro­inflammatory cytokines.