Cytokine levels as markers of wound healing and treatment of purulent wounds in children

Abstract

Today, the problem of preventing the chronicity of wound processes in both adults and children remains urgent, the search for effective methods of empirical treatment of purulent and infected wounds. Among all mediators of inflammation in the most studied in injuries and other infected and sterile injuries in children, adults belong to interleukins: interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin -10 (IL-10) and tumor necrosis factor α (TNF-α). These cytokines are mediators of processes aimed at the regulation of repair processes in the wound. The goal is to study the level of pro-inflammatory and anti-inflammatory cytokines in dynamics in the treatment of infected and purulent wounds in children using the proposed optimized local treatment compared to the standard technique.