Synthesis and Biological Activity of 8-Benzylidenehydrazino-3-Methyl-7-β-Methoxyethylxanthines
| dc.contributor.author | Romanenko, N. I. | |
| dc.contributor.author | Pakhomova, O. A. | |
| dc.contributor.author | Ivanchenko, D. G. | |
| dc.contributor.author | Kamyshnyi, A. M. | |
| dc.contributor.author | Polishchuk, N. N. | |
| dc.contributor.author | Романенко, Микола Іванович | |
| dc.contributor.author | Іванченко, Дмитро Григорович | |
| dc.contributor.author | Поліщук, Наталія Миколаївна | |
| dc.date.accessioned | 2021-11-16T14:09:04Z | |
| dc.date.available | 2021-11-16T14:09:04Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | A simple preparative synthesis of 8-hydrazino-3-methyl-7--methoxyethylxanthine was developed. Reaction of the obtained hydrazinoxanthine with aldehydes and ketones produced several previously undescribed 8-ylidenehydrazino derivatives of 3-methyl-7--methoxyethylxanthine. PMR spectroscopy confirmed the structures of the synthesized compounds. Biological tests established that several of the synthesized compounds had pronounced antimicrobial, antifungal, and antioxidant activity and could be recommended for further research. | uk_UK |
| dc.identifier.citation | Synthesis and Biological Activity of 8-Benzylidenehydrazino-3-Methyl-7-β-Methoxyethylxanthines / N. I. Romanenko, O. A. Pakhomova, D. G. Ivanchenko, A. M. Kamyshnyi, N. N. Polishchuk // Pharmaceutical Chemistry Journal. - 2014. - Vol. 48, № 7. -P. 444-447. - https://doi.org/10.1007/s11094-014-1128-1 | uk_UK |
| dc.identifier.uri | https://zsmu.rosbai.com/handle/123456789/15435 | |
| dc.language.iso | en | uk_UK |
| dc.subject | xanthine | uk_UK |
| dc.subject | synthesis | uk_UK |
| dc.subject | antioxidant activity | uk_UK |
| dc.subject | antimicrobial activity | uk_UK |
| dc.subject | antifungal activity | uk_UK |
| dc.title | Synthesis and Biological Activity of 8-Benzylidenehydrazino-3-Methyl-7-β-Methoxyethylxanthines | uk_UK |
| dc.type | Article | uk_UK |